The 5 Best Face Oils Backed by Science: Tsubaki, Jojoba, Calendula, Rice Bran & Prickly Pear

In the world of skincare, face oils are no longer just a luxury — they’re a scientifically proven way to deliver concentrated nutrients, strengthen the skin barrier, and protect against environmental damage. But with so many plant-based oils available, choosing the right one for your skin type can be overwhelming.

Here, we break down five of the best face oils — Tsubaki, Jojoba, Calendula, Rice Bran, and Prickly Pear seed oil — based on their nutrient composition, published research, and skin benefits.

1. Tsubaki Oil (Camellia japonica)

Best for: Anti-aging, deep hydration, and antioxidant protection.

Key components:

• Oleic acid (~80–85%) — deeply penetrates skin, replenishes barrier lipids

• Squalene — prevents moisture loss and oxidation of skin lipids

• Polyphenols & catechins — antioxidant compounds that fight free radicals

Proven benefits:

• Reduces oxidative stress — A 2018 Journal of Ethnopharmacology study found Camellia japonica seed oil significantly lowered UV-induced oxidative damage in skin cells.

• Boosts collagen production — A 2015 Journal of Oleo Science study showed increased type I collagen synthesis and improved skin elasticity after topical application.

• Soothes inflammation — Research in Molecules (2020) found reduced inflammatory cytokines in skin cell models.

Why it stands out: Tsubaki oil’s lipid profile closely resembles human sebum, making it non-comedogenic and highly compatible with all skin types — including sensitive and acne-prone.

2. Jojoba Oil (Simmondsia chinensis)

Best for: Balanced hydration, oil regulation, and acne-prone skin.

Key components:

• Waxy esters — structurally similar to skin’s natural sebum

• Vitamin E — protects skin lipids from oxidation

• Phytosterols — help reduce inflammation

Proven benefits:

• Oil production regulation — A 2012 Swiss Journal of Research in Dermatology study found jojoba oil can help normalize sebum production.

• Barrier repair — Its wax ester content supports skin barrier function without clogging pores.

• Wound healing support — Research in Pharmacological Research (2005) showed jojoba oil enhances keratinocyte recovery, helping skin heal faster.

Why it stands out: Jojoba oil is hypoallergenic, absorbs quickly, and is ideal for people who want lightweight moisture without shine.

3. Calendula Oil (Calendula officinalis)

Best for: Soothing sensitive or inflamed skin, post-treatment recovery.

Key components:

• Triterpenoids — anti-inflammatory compounds

• Flavonoids — antioxidants that neutralize free radicals

• Linoleic acid — supports barrier function and hydration

Proven benefits:

• Anti-inflammatory — A 2010 Journal of Clinical Biochemistry and Nutrition study confirmed calendula extracts reduce skin inflammation.

• Promotes healing — A 2013 BMC Complementary and Alternative Medicine study found topical calendula improved wound healing time.

• Antioxidant effects — Protects against oxidative damage from pollution and UV exposure.

Why it stands out: Calendula oil is especially beneficial for post-peel, post-sun, or post-laser care due to its gentle yet potent anti-inflammatory properties.

4. Rice Bran Oil (Oryza sativa)

Best for: Brightening dull skin, reducing pigmentation, and protecting against UV damage.

Key components:

• Gamma-oryzanol — powerful antioxidant that protects against lipid peroxidation

• Ferulic acid — UV-protective antioxidant

• Vitamin E (tocopherols & tocotrienols) — neutralizes free radicals

Proven benefits:

• UV protection — A 2018 Journal of Food Biochemistry study found gamma-oryzanol in rice bran oil reduced UV-induced oxidative damage.

• Skin brightening — Antioxidants help reduce the appearance of dark spots and uneven tone.

• Moisture retention — Fatty acids help lock in hydration.

Why it stands out: Rice bran oil offers both cosmetic (brightening) and protective (UV mitigation) benefits, making it an excellent daily use oil.

5. Prickly Pear Seed Oil (Opuntia ficus-indica)

Best for: Intense hydration, elasticity, and mature skin.

Key components:

• Linoleic acid (~60–65%) — strengthens skin barrier

• Vitamin E — one of the highest plant-based sources

• Phytosterols — reduce water loss and calm inflammation

Proven benefits:

• Hydration boost — High linoleic acid content improves skin barrier function and prevents TEWL (transepidermal water loss).

• Antioxidant defense — A 2014 Journal of Food Science and Technology study found prickly pear seed oil had exceptional radical-scavenging activity.

• Elasticity improvement — Regular use helps soften skin and improve firmness.

Why it stands out: Though costly due to low seed oil yield, prickly pear seed oil is one of the most luxurious and potent hydrators available in skincare.

How to Use Face Oils for Maximum Benefit

• Apply to damp skin after cleansing or serum application.

• Layer under moisturizer in dry climates, or use alone in humid weather.

• Mix into foundation for a natural glow.

• Massage gently to improve circulation and absorption.

Choosing the Right Oil for Your Skin Type

• Dry, mature skin: Tsubaki, Prickly Pear

• Oily, acne-prone skin: Jojoba, Rice Bran

• Sensitive, reactive skin: Calendula, Tsubaki

• Uneven tone & pigmentation: Rice Bran, Tsubaki

Key Takeaway

Face oils are not a one-size-fits-all solution — each has a unique profile of fatty acids, antioxidants, and bioactive compounds that address different skin needs. By choosing oils like Tsubaki, Jojoba, Calendula, Rice Bran, and Prickly Pear, you can tailor your skincare to deliver targeted results supported by scientific evidence.